MSYS2 is basically Cygwin with Pacman for package management, plus several other environments with either GCC or Clang and different Windows-Native C and C++ runtimes.

It's nice, but not perfect. It inherits a lot of problems from Cygwin. File access is still slow (as mentioned in other threads) and symlinks don't behave right (by default making a symlink creates a deep copy of the target, and even NTFS symlinks need to know whether the target is a file or a directory; either way you cannot create a symlink when the target is missing, and this causes rsync to fail, for example.)

MSYS2's strength is as an environment for compiling cross-platform apps for Windows, and I would recommend WSL2 for anything else.