Overuse of CT scans could cause 100k extra cancers in US
icr.ac.uk
icr.ac.uk
From the paper itself: "We projected future lifetime radiation-induced cancer risk using the National Cancer Institute’s Radiation Risk Assessment Tool (RadRAT) software version 4.3.1, which utilizes risk models from the National Academy of Sciences’ Biologic Effects of Ionizing Radiation (BEIR) VII report for 11 site-specific cancers ... using a more recent follow-up of the Japanese atomic bomb survivors and pooled analyses of other medically exposed cohorts."
So I wouldn't hang my hat on the claim "that CT examinations in 2023 were projected to result in approximately 103,000 future cancers over the course of the lifetime of exposed patients."
Are CTs without risk? Of course not but quantifying that risk isn't easy with the data and models we have available. We should be glad that the authors are trying to do so but also be cautious about publicizing their estimate as an eye-catching headline. Since most who read the headline will over interpret it as an established scientific fact that meets a higher level of evidence than has actually been met.
Head CT scan is towards bottom of green chart
Here's a relevant moment from the MIT OpenCourseware Nuclear Engineering lecture about ionizing radiation damaging DNA: https://www.youtube.com/watch?v=HfRpkTG7Iow&t=30m30s
I can't recommend that course enough if you're interested in radiation physics.
This is a nonsensical point because it can trivially both be true that cancer rates fall overall while CT scans cause additional cases of cancer. The comparison has to be, and that's what the original paper did, how many additional cases of cancer do you get from radiation in particular, that is to say cancer incidence could obviously be even lower all other things being equal.
[0] https://pmc.ncbi.nlm.nih.gov/articles/PMC2672242/
[1] https://jamanetwork.com/journals/jamainternalmedicine/fullar...
> In the UK, regulations mean that CT scan requests are reviewed by radiologists and only carried out when clinically justified and with optimised doses. Because of this, the UK has one of the lowest rates of CT scans per population in OECD countries – less than 100 scans per 1,000 people, compared with over 250 scans per 1,000 people in the US. Research studies have provided evidence that CT scans used in targeted screening on healthy people, such as for lung cancer, will save lives, and that the benefits outweigh the risks.
> However, the researchers argue that the risk of cancer outweighs any potential benefit from the whole-body scans offered by private clinics to healthy people.
So the authors do agree that "targeted screening of healthy people" done right is beneficial even though CT scans are seen as a risk-inducing measure, yet this isn't true if you just go and sell whole-body scans to healthy people, which tells me that "CT scan" may not be precise enough a word to know what the risk-benefit ratio might be in a given case; you'd have to at least add what body part was scanned, why, and maybe even where: if an American tells you they got a CT scan chances are apparently higher they just got sold an expensive and risk-inducing full-body shotgun diagnosis with little chance of turning up anything while when a Brit tells you the same, chances are higher that an experienced person tasked with saying no when in doubt vetted risks and benefits and concluded a focused exposure was worth it.
"The current average effective dose of a CT study is ∼10mSv, with the implementation of dose reduction techniques discussed herein; it is realistic to expect that the average effective dose may be decreased by 2–3 fold." 2010 https://www.ejradiology.com/article/S0720-048X(10)00311-6/fu...
It would be neat to see a chart of the average effective dose of CT studies over the past 40 years. And any accounting of how much it declined as a result of Moore's law and software improvements for producing the "Computed Tomography."