(1) Have a good marriage, children who do well, and "live happily ever after", a MUCH bigger challenge than I expected.
My experience is that a significant fraction of women just do NOT want anything like the standard marriage vows, e.g., would rather get alimony and then be an alcoholic cat lady.
My guess is that (a) long each woman lived in a small tribe all in one open (no partitions) house, maybe 20 yards wide, 60 yards long, half-pipe, that is, semi-circular arches for both the walls and ceiling, much like a WWII US Army Quonset hut except made of wood and straw, intended to keep in warmth and keep out weather and wild animals. There the women served needs of the tribe, got their security from the tribe, and were loyal to the tribe and (b) are now suffering from missing (a). I.e., the nuclear family is not natural and is held together, weakly, mostly only by the cash economy, jobs, ownership, etc.
(2) Achieve AGI, artificial general intelligence.
(3) World peace, prosperity, health, and happiness.
(4) Automation so that machines work and humans live good lives.
(5) Make sense out of quantum mechanics -- sorry, physics experts, sorry, but sorry, from reading the best there is on quantum mechanics, von Neumann, Griffiths, etc., to my mind from my math Ph.D., the math of quantum mechanics just does NOT make good sense.
We can start with the simple theorem of Fourier theory, the uncertainty principle, and then what physics does with it, e.g., claims that empty space can spontaneously erupt with energy. Uh, from Fourier, Riemann, Lebesgue, Rudin, the Fourier transform of 0 is 0 -- simple.
Also the claims of superposition make no sense, e.g., one electron can be in two places at once -- suddenly with twice the mass, charge, momentum, and energy? Add some more beam splitters and the electron can be in 64 places at once with 64 times as much mass, charge, momentum, and energy?
And have some clear technical writing, e.g., what are "quantum numbers"? Need definitions, explanations, examples, the usual in technical writing.
E.g., actually give what would be in the math of, say W. Rudin, an actual clear DEFINITION of a wave function as an actual function, with domain, range, etc. For each wave function, and d > 0, there are points x and y where the wave function is non-zero and the distance between x and y is greater than d?
(6) Make sense out of space, the vacuum, e.g., how it enforces conservation of energy, momentum, etc.
(7) Make sense out of the Big Bang.
(8) Do some stochastic process math to say how DNA makes evolution proceed at the speed it does.
(9) Finally make progress on P versus NP.