That's not how most basic science works. It's easy with hindsight to identified research that didn't work or seemed dumb at the outset, but some small percentage of exploratory projects turn out to be major advances. Studying algae ion channels was not intended to be applied research but ended up with the discovery of green fluorescent protein, which won a nobel prize and opened the door to immunohistochemistry, optogenetics, and other crucially important biomedical advances. There are countless examples like this. It's trivially easy to find failed research too... but that's the process. It's only expensive if you ignore all of the innovation that comes downstream of the initial grant process.