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I tried creatine. Taking it in powder form mixed with my protein shake made me feel awful.

Not worth it. Seemingly does nothing.

Don't take it on an empty stomach. Don't do the overload the first 10 days, instead stick to just 5g daily. It will take a little longer to get the full effect of the loading stage but with far less risk of stomach upset.

I have more issues with it when there's food in my stomach vs when there's not. In fact if I eat anything within 15 minutes (in either direction) of consuming creatine, I will for certain have diarrhea. I have zero issues with it on an empty stomach. These days I just make sure not to eat anything within an hour of the creatine and I'm good.

Agreed on the loading phase. It's not worth it.

EDIT: should add that I've been taking creatine for several years

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