yes I think we're okay with divs not being centered some of the time.
many millions have been spilled to adjust pixels (while failing to handle loads of more common issues), but most humans just care if they can eventually get what they want to happen if they press the button harder next time.
(I am not an LLM-optimist, but visual layout is absolutely somewhere that people aren't all that picky about edge cases, because the success rate is abysmally low already. it's like good translations: it can definitely help, and definitely be worth the money, but it is definitely not a hard requirement - as evidence I point to the vast majority of translated software.)
I think there's overwhelming evidence that it's not truly necessary.
Maybe in an alternate universe where every user-agent enabled browser had this type of thing enabled by default, most companies would skip site design all together and just publish raw ad copy, info, and images.