A breakthrough moment: Researchers discover new class of antibiotics

A good week for the battle against microbial pathogens!

A new class of antibiotics referenced in the article above:

Jangra, M., Travin, D.Y., Aleksandrova, E.V. et al. A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome. Nature (2025). https://doi.org/10.1038/s41586-025-08723-7

And a new anti-fungal! We've only got a handful of these:

Deng, Q., Li, Y., He, W. et al. A polyene macrolide targeting phospholipids in the fungal cell membrane. Nature (2025). https://doi.org/10.1038/s41586-025-08678-9

Seems like promising new science in an area that is an under appreciated health risk. in a perfect world, the science should be the hard part. But where we have been for a while, the economics of antibiotic drug development and commercialization are a significant challenge. I hope this gets due traction.