We wanted to use Ractors in our latest Ruby project (which is Rust based using rb-sys/magnus for some parts), but since our users use Google Protobuf inside the code that may run in Ractors, we could not because the library is not Ractor safe[0] (and it's unreasonable for us to ask our users to not be able to use the official Protobuf library).
0 - https://github.com/protocolbuffers/protobuf/issues/19321