I went to see the largest / one of the oldest beeches a couple years back and it had died presumably of this disease. I visited another old growth forest in Pennsylvania too and all the old growth beeches there were dead. In fact, in that forest, though it had never been logged the only large old growth trees I could find more than one or two of, were hemlocks. The chestnut, elm, ash, and now beech all having been taken by newly introduced diseases.
Plants don't have an immune system, at least the way we normal think of one. As far as we know, there isn't a way to "vaccinate" them against diseases. Maybe that will change with molecular techniques, but not today.
I'm looking for land to buy. I won't see my trees reach maturity, but hopefully I can get them established.