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Unless they are focused on decreasing bloat, I don't think that this will happen. There are lots of utilities and other software that still uses GTK2. I doubt that GIMP was the last tool left to prevent dropping GTK2. I found this from ArchLinux, search for "gtk 2":

https://wiki.archlinux.org/title/Uniform_look_for_Qt_and_GTK...

Plus you can search for "GTK 2" dependencies. Some sites seem hopeful to move to GTK 4, while others wish they could move to 3, and some talk about upcoming 5.

Without GIMP using it any more releases is unlikely.

The more interesting thing is that GIMP 3 has allowed distros to drop Python 2 completely. Fedora has done it recently.

Debian and RHEL already did.

I don't know about RHEL but gtk2 is still in Debian unstable[0].

A reverse dependency search shows 340 packages relying on it (200 direct dependencies).

[0] https://packages.debian.org/sid/libgtk2.0-0t64

And FreeBSD Ports has 434 extant ports which depend on it https://www.freshports.org/x11-toolkits/gtk20/

Hmm, there have been discussions about doing it, but I guess they are moving slowly.