I don't need to be told to RTFM. I was asking for advice. My attention span is my most valuable commodity, and since I'm not really surprised or slowed down by setuptools, etc., it sounds like uv probably isn't worth investigating.
Thanks.
To answer my own question—and to actually help other people with similar use cases—I read about uv's build process and dependency locking. It does not appear to be able to lock dependencies for build distributions (wheels).
https://docs.astral.sh/uv/concepts/projects/build/
https://docs.astral.sh/uv/pip/compile/
However, it does mention that Python supports multiple build systems, which I didn't know, so this hasn't been a complete waste of my time.
Thanks!