There's going to be a lot of "the big successes already happened" type comments about YC but I think they're wrong.

Sure all big successes are unique in time, and entrepreneurship & web tech are mainstream now. But there's still lots of industries to disrupt. What gets harder is that the level of expertise needed to disrupt an industry is now much higher. You didn't need to work in hotels to create Airbnb, or a bank to create Stripe, or deliveries to do Doordash, etc. A bunch of scrappy web founders that were hosts, or trying to sell on the internet was expert enough to get started. This may be changing in important ways, but huge successes will surely happen.