USAid cuts could create untreatable TB bug 'resistant to everything we have'
theguardian.com
theguardian.com
Unlike more virulant diseases (think, say, Ebola), TDR-TB transmits slowly, but steadily, especially under conditions of poverty (overcrowding, poor ventilation, poor hygiene), many carriers are asymptomatic (we've seen what this does with Covid-19), and there is no cure.
The only treatment is to give patients free and isolated housing, plus food, clothing and entertainment. As a friend noted, "If you execute them or put them in prison cells and feed them slop nobody goes to the doctor if they have a cough." (See: <https://web.archive.org/web/20230531181139/https://old.reddi...>).
TDR-TB already exists in places such as India.
If an uncontrolled outbreak were to emerge in one of the world's poor megacities, places such as Dhaka, Bangladesh; Cairo, Egypt; Kinshasa, Democratic Republic of the Congo; Lagos, Nigeria; Karachi, Pakistan; Delhi, or Mumbai, or Kolkata, India; Jakarta, Indonesia; Metro Manila, Philippines; Mexico City, Mexico; Ho Chi Minh City, Vietnam; Luanda, Angola; or in other places with public health systems which are already dysfunctional and are now under further direct attack, such as the United States of America, it's going to be a very, very, very troubling future.
Cutting USAID is already beyond idiotic and short-sighted. This is simply suicidal.
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Notes:
1. See e.g., <https://web.archive.org/web/20230531181139/https://old.reddi...> <https://news.ycombinator.com/item?id=6640362>.
You must not just stay away from infected people. You should never go anywhere an infected person HAS BEEN in the last few months, with the potential exception of open air spaces.
We wouldn't have face masks. We'd be back to deporting infected people to remote islands to die.
Technically there is a cure for TB: cutting up people's lungs. The individual bacteria grow so large there's a decent success rate for literally cutting them out one-by-one ... obviously it does not exactly restore your previous life expectancy, and it's not a guarantee.
It's the equivalent of standing in front of a pool of vomit with an armful of mops while saying "hmmm, why do I gotta be the one to clean this up?"
From TFA.
Millions of dollars in spending ($250m -- $400m/yr, from TFA) will generate trillions of dollars in savings through avoided pandemics. The Covid-19 pandemic cost the US $14 trillion through the end of 2023:
<https://healthpolicy.usc.edu/research/covid-19s-total-cost-t...>
Curtailing funding without a planned drawdown or transition to other forms of support strands and makes useless assets including laboratories, screening centres, healthcare workers, and far, far, far more. The approach taken is, as I've already described, simply suicidal.
Those with an capacity at comprehending basic English and applying elementary reasoning skills are encouraged to read a NY Times article which spells out the impacts of the aid curtailment on the US and its citizens and residents:
"How Foreign Aid Cuts Are Setting the Stage for Disease Outbreaks"
Dangerous pathogens left unsecured at labs across Africa. Halted inspections for mpox, Ebola and other infections at airports and other checkpoints. Millions of unscreened animals shipped across borders. The Trump administration’s pause on foreign aid has hobbled programs that prevent and snuff out outbreaks around the world, scientists say, leaving people everywhere more vulnerable to threatening viruses and bacteria. That includes Americans.
<https://www.nytimes.com/2025/03/07/health/usaid-funding-dise...>
Archive: <https://archive.is/yvMly>
they are pretty much desperate!
__________________ google translation ___________
Dear all, I am writing to you from Lacor, where I arrived a few days ago.
In addition to the challenges that we have been facing for many years together with the hospital staff, there is another challenge that was unimaginable until a few weeks ago: the blocking of funds from the US agency USAID. For over twenty years, USAID has financed the life-saving program for HIV-positive people, that is, prevention, diagnosis and above all the expensive treatment of HIV patients.
Yesterday, March 6, we received the letter that puts an end to the hopes of continuing to receive at least the precious drugs.
For Lacor, this means a loss of approximately 600 thousand dollars a year. The antiretroviral drugs alone that were guaranteed to the 7 thousand HIV-positive people being treated at Lacor had a value of 400 thousand dollars. A sum equal to the cost of all the other drugs needed to treat the rest of the 190 thousand patients that the hospital receives every year.
In addition, Lacor received approximately 200 thousand dollars to cover the salaries of approximately 40 employees involved in the care of HIV patients.
Costs that Lacor, already in crisis due to the exceptional increases caused by the pandemic and the geopolitical situation, cannot afford. The Foundation, which meets the needs in times of crisis, cannot even cope with further figures of this magnitude.
Since yesterday, Dr Emmanuel Ochola, scientific director and head of the HIV program at Lacor, has stopped outreach, missions for check-ups and the distribution of drugs to those who live in distant villages.
In a few days we will run out of antiretroviral reserves in the hospital.
For me, for all my Ugandan and Italian colleagues, health workers and otherwise, who share with me the happiness and responsibility of this work, these are not faceless people who live on the other side of the world. They are women who have worked in the hospital for decades, who support their families. Women who I remember reduced like my mother to a skeleton, sick every other week until, in 2004, this program was started.
With antiretrovirals they started living again, they had children... now the thoughts and worries are crazy.
But it is just another of those diseases that here in Uganda lead to death, while in Italy they are quickly and simply resolved.
Without antiretrovirals, HIV is a death sentence and again a great danger of spreading the virus.
We are looking for solutions to stem the emergency, but the blanket is short, the resources increasingly stretched.
It's bad USAid stopped funding this but can you tell me that in a less infuriating way please?
I mean here obviously the bug creates itself through an evolutionary process. USAid had been doing great work to make this less likely, and now they've stopped. That doesn't mean the cuts create the bug!
Not directly, but by creating the exact scenario that cause then to be created..
The USAID funds cut will cause patients to have to stop their treatment half way because there are no more money to buy the drugs required to their treatment..
This is the basic recipe to a drug resistant viruses...
When you start a treatment the first to die are the copies of the virus that are susceptible to the drug while the more resistant copies take longer to die..
This is why is so important to keep a treatment even after the symptoms ended, there will still be copies of the virus in your body that are resistant to the drug but not enough copies to cause the disease..
If you stop the treatment half way the copies that are resistant have the opportunity to multiply again, but now the drug will have less effect on it..
Repeat this process enough and you get a strain of the virus that is immune to the drug..
Repeat the process again and again with other drugs and you get a strain that is immune to everything..
With the number of patients affected by USAID cuts means it is practically guaranteed that a drug resistant strain will happen..
> The WHO and UN have set targets of eradicating the disease by 2030, but even before the US aid decision, there was an $11bn shortfall in the global response.
So even without the usaid money, we're still at an $11bn shortfall due to rounding! Nice try, Guardian!
The whole world is shocked and awed that we stopped paying while holding out empty wallets themselves.
The US isn't an empire in decline...it was given away!