A friend of mine that has kids said that once you have kids, there's no such thing as going on vacation. You're just being a parent somewhere else.[0]
I personally am skipping the side-quest of parenthood, but have certainly seen his claim play out. My wife and I were at Universal Studio Hollywood, and some couple had a baby in a carriage that wouldn't stop crying, and I just couldn't help but think...imagine spending hundreds or even thousands of dollars to go on vacation, and you still gotta deal with a screaming baby.
I couldn't deal with that.
[0] For anyone saying "Just let the grandparents/some other family take them for the week", this isn't an option for everyone for various reasons. In my friend's case, it's because he lives in London, but his parents live in the USA, and his in-laws live in Malaysia.