Clojure is running in a live system in a big veterinarian hospital
groups.google.com
groups.google.com
Where there is fear, there are opportunities.
And yes the rules, and crazy laws, and hand waving are very very apparent. Its insane but we make plenty of money.
I'm a one-man startup working to solve problems in the clinical trial and research space. The sheer number of problems can be somewhat distracting and the rules daunting, but there are a lot of doctors out there with money to throw at solutions. It is amazing.
Am I profitable? Not yet. Obviously, I'm missing some necessary traits (read: co-founder.)
I am certainly not an advanced programmer, I would like a pointer to some resources on the subject.
edit: Naughty Dog is a successful game company that used Lisp, but with a OO style: http://c2.com/cgi/wiki?LispInJakAndDaxter