The only problem I have with a comment like this is that there were millions of factors and pieces to the puzzle of creating Facebook, that this is a ridiculous over simplification of how it came to be.
Luck, timing, market condition, state of competition etc...
Zuck is the luckiest person alive to have been in the place he was when he was - its not like he simply invented everything required to make Facebook from zilch. Friendster and MySpace verified the market, zuck had a great twist on that and a million other thing fell into place.
Not to say it was simple and non-trivial, but that comment just has way too much bravado and ego and is just plain stupid.
He did a great job, but there is nobody else who should be using that line in any other context.