C got its performance fame thanks to optimizing compilers that abuse UB semantics.
Microsoft team on .NET, especially the great Stephen Toub blog posts, has been showing off how much performance can be squizzed out of a managed language compiler toolchain when people actually care.
Also lets not forget Apple only moved away from Object Pascal due to an internal team doing MPW initially as kind of submarine project, due to their UNIX roots, and still their focus was C++, not C.
Toy systems, yes. Hey, I too, think CircuitPython is really neat. But I'm skeptical someone would base a PLC (or similar) on it.
The James Webb Space Telescope runs JavaScript, apparently [1].
[1]: https://www.theverge.com/2022/8/18/23206110/james-webb-space...