Simulating 500M years of evolution with a language model

preprint, https://www.biorxiv.org/content/10.1101/2024.07.01.600583v2

previous discussion, https://news.ycombinator.com/item?id=40787800

The proteins that exist today have developed into their present forms over the course of billions of years of natural evolution, passing through a vast evolutionary sieve.