I expect that jank will be migrating from C++ to Rust, at some point. https://github.com/jank-lang/jank
It'll have its first alpha release this year. It's currently written in C++, but will be migrated to Rust piece by piece, either once we find a champion to lead it or once we reach Clojure parity and I can focus on it. C++ interop will remain, but we'll benefit from Rust's memory safety and improved dev tooling.
I randomly came across the talk from the founder, and their reasoning for this was awesome: basically creating a C++ REPL for the science community (and the rest of us by happy accident).
If it is about additional safety, in any regard, self hosting would be the answer, not Rust.