Here's a tip: if "retarded" is the best adjective you can come up with, you've already lost the argument.
As much as I appreciate river_styx's contribution to the development of River's Law, I really think my mental flight of fancy is superior. Or at the very least would make for a better motivational poster:
"Don't Say 'Retarded', Or She'll Kill You With Her Brain"
Be clear though that I was attacking the argument itself, not the poster.