I agree, and wrote a rant about this as part of the post: https://eli.lipsitz.net/posts/introducing-gamebub/#a-brief-r...
IMO: the only real advantage is that it allows you to meet the precise timing needed to interface with physical hardware, like cartridges and other consoles (with link cables).
I think they're also really fun to write, because you think more like a hardware designer than a software engineer.