Chamber pressure in a .22 cal pistol is on the order of 20,000 PSI [1] The tensile strength of thermoplastic at standard temperatures is 1/2 that [2] and it goes down as the temperature goes up (its a thermoplastic for a reason). Firing a .22 caliber round using gunpowder would destroy the barrel on the first firing.
Now I could believe you built the receiver and triggering mechanism on a thermoplastic printer, but not the actual firing chamber.
[1] http://www.lasc.us/SAAMIMaxPressure.htm [2] http://www.engineeringtoolbox.com/physical-properties-thermo...