The topic of the 6502 ISA simplicity is a pet peeve of mine, because to me it's clear that anybody thinking that such simplicity is a good thing, never progressed past a hello world.

Programming anything of moderate complexity on the 6502 is hard. 8 bits are way too restrictive (e.g. screen addressing on the Commodore 64). Multiplications/divisions need to be hand-rolled. And even 16 bit sums/subtractions are simple but still not trivial to perform efficiently.

The 8086+DOS platform is way easier to work on, in comparison (if one wants to learn basic assembly).