Adhibin identified as an active agent against cancer metastasis

Could be massive, if holds true. Metastasis is the killer.

>> In his working group, Professor Tsiavaliaris is conducting research into myosin motors. These motor proteins are mini-machines that drive many vital processes in our cells, including force and movement. They transport small 'packages' within the cell and interact with the cytoskeleton, a dynamic scaffold of filaments and tubes that extends from the cell nucleus to the cell membrane.

>> In addition, myosins reduce the activity of Rho GTPases and are therefore particularly interesting as anti-metastatic targets.

>> "My research team has discovered a synthetic agent called Adhibin that inhibits the motor function of myosins and thus inhibits the Rho proteins even more," says the biochemist. This suppresses the Rho-GTPase-mediated mechanisms of metastasis.

>> As a result, tumor cells can no longer migrate undisturbed and cannot attach themselves to other sites.