Here's me thinking it would be some open source artificial heart designs.
4B years, yes, but evolution is a pile of kludges on top of kludges.
I don't just mean fat storage algorithms leading to metabolic syndrome and T2D, but for example whether we could afford to have better immune and musculoskeletal systems, more cancer-fighting cells, better regeneration etc if we were tuned to an energy budget of 3000kcal instead of 2000kcal.