To me, the most concerning fact is that science itself has become politicised, and as a consequence science denialism is gaining more and more traction. To me, that seems like a potential tragedy for our entire civilization. Even more so if it leads to magnifying the biases in science as it becomes a part of the battlefield of politics. This is really bad.
More personally, as an LGBT person, it's concerning to me that the science they take the most issue with is just stuff like "gender dysphoria is real and trans people deserve compassion", "sex brain differences are statistical, not qualitative, and maybe we shouldn't force people into strict gender roles", or even just "yeah, misogyny is real" and "there's nothing wrong with gay people".