Our NX is pointed to store artifacts in GHA, but our GHA scripts don't do any caching directly, it is all handled by NX. It works so well I would even consider pulling a nodejs environment to run it in non-nodejs projects (although I haven't tried, probably would run into some problems).
It is somewhat heavy on configuration, but it just moves the complexity from CI configuration to NX configuration (which is nicer IMO). Our CI pipelines are super fast if you don't hit one of one of our slow compilling parts of the codebase.
With NX your local dev environment can pull cached items that were built from previous CI ran-jobs or other devs. We have some native C++ dependencies that are kind of a pain to build locally, our dev machines can pull the built binaries built by other devs (since all devs and CI also share the same cache-artifacts storage). So it makes developing locally a lot easier as well, I don't even remember last time I had to build the native C++ stuff myself since I don't work on it.