This one stands out to me because, as they say, “the dose makes the poison”. Taking some trace element from something “natural” and highly concentrating it is basically as novel as something new. Consuming a gram of something over a lifetime is different than consuming a gram of something every day.
Also, eating something for hundreds of thousands of years only means that most people will live several decades while eating it. It doesn’t mean people won’t be killed by it. It doesn’t mean people wont get cancer from it in 30-40 years. Killing 1% of the people that eat something would be a perfectly acceptable evolutionary loss, depending on the amount of nutrition and calories provided.
That’s why it is an appeal to nature fallacy. Because it says absolutely nothing about population level long term health effects.