They’re similar, but DuckDb is more of a batteries-included database whereas DataFusion is an embeddable query engine. You can use DuckDb in embedded-ish scenarios, but it’s not primarily targeting that use case. To put it another way, DataFusion is sometimes described as “the LLVM of databases.”
Another difference is that DuckDb is written in C++ whereas DataFusion is in Rust, so all the usual memory-safety and performance arguments apply. In fact DataFusion has recently overtaken DuckDb in Clickbench results after a community push last year to optimize its performance.