Amusingly enough, the main direction Shepherd is exploring right now is integrating Spritely Goblins (the folks that are also writing Hoot), so that it would have a distributed, capability-based process manager. I wouldn't say running Shepherd with Hoot is a direct goal of this, but it may fall out naturally from it.
Shepherd may actually work in Hoot right now -- I know the Spritely team were working on getting Guile's fibers library to work in WASM, and that's probably the biggest lift.