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Just to clarify metabolic syndrome isn't the umbrella term for all of these things.

Metabolic syndrome is when you have 3 or more of: central adiposity, high blood pressure, high blood sugar, high triglycerides and low HDL.

You can have any of these independently, it becomes metabolic syndrome when you hit the bingo.

Those are the most obvious and easy to spot signs. Metabolic syndrome is dysfunction at the mitochondrial level.

> Metabolic syndrome is dysfunction at the mitochondrial level.

It might or might not be involved. At this point, it's not clear. Obesity and insulin resistance are the most likely proximate causes.