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I think this is an accurate point. I would also add preservatives. Companies have an incentive to increase shelf-life, so they pump these products full of them, despite their effects on health.

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What evidence is there of preservatives having detrimental effects on humans (in the doses we actually receive)?

Preservatives achieve their intended function by broadly destroying and preventing the growth of microbes, which are an integral part of our digestive system. So I would flip the question: what evidence is there that preservatives don't damage a healthy human microbiome?

Here is a review of some of the research. It seems to still be an open question because of the many variables involved: https://pmc.ncbi.nlm.nih.gov/articles/PMC9864936/

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