Ultimately, that nothing ultimately matters, also does not really ultimately matter.
All we really have is now, and the conditions which have led to now, and our ability to do things within our power now. And that does matter, as much as anything ever can. Which is something. Getting through to that point is not a given.
IMO, part of what made the Buddha, well, the Buddha, is he tried to make it better. Despite knowing all this. And despite it being much, much harder, messier, and more painful than the path he could of taken - which is opting out.
Will you make it better (in your judgement)? Make it worse (in your judgement)? Rely on someone else’s judgement? How accurate is your judgement?
Or opt out (and what does that mean)?
Buddha (depending on the tradition) taught a path to reduce pain, and in some cases opt out (for Monks, at least, to some extent) by hopefully seeing the truth as best as one can.
That form of Buddhism is not very popular.
Religions that give a narrative involving conquering (Islam, Christianity in the recent past), surrendering (Modern Christianity, Jainism), or being chosen/made (Judaism/Hinduism) for/by a deity to achieve heaven or have one’s fate decided are much more popular.
I expect for much the same reason that action movies, dramas, and epics are more popular than quiet walks in the woods.