I can’t find it right now but I read a great comment on legalization that pointed out that a kid experimenting with weed and cocaine in college is doing so for a radically different reason than a kid doing it escape the daily misery of his ghetto neighborhood.
This is also why you’ll often see staunch opposition to legalization in the lower socio-economic classes, with them having seen people close to them destroyed by drug use.
And yes, legalization and regulation would of course also allow harm reduction. But it is good to be able to take the opposition’s perspective :)