"Photocatalytic C–F bond activation in small molecules and polyfluoroalkyl substances" (2024) https://www.nature.com/articles/s41586-024-08327-7 :

> Abstract: [...] Here, we report an organic photoredox catalyst system that can efficiently reduce C–F bonds to generate carbon-centered radicals, which can then be intercepted for hydrodefluorination (swapping F for H) and cross-coupling reactions. This system enables the general use of organofluorines as synthons under mild reaction conditions. We extend this method to the defluorination of polyfluoroalkyl substances (PFAS) and fluorinated polymers, a critical challenge in the breakdown of persistent and environmentally damaging forever chemicals.