Email spam is repetitive enough that the usual Thunderbird filters work. If a spam email has an unsubscribe link, I click on that and add the sender to the block list. If it doesn't have an unsubscribe link, I try to find out which service sent it and send them a notice of a CAN-SPAM law violation. The usual suspects (Mailchump, SpamGrid, etc.) do terminate accounts for that, to prevent being blocked themselves.