In the apps I've written, generally the user interaction with the API is synchronous and has some immediate effect (e.g. uploading a file - the file is committed and guaranteed accessible by the time the HTTP success response is sent, giving the system strong causal consistency) and within that same transaction I enqueue the related background task (e.g. processing the file) so that we never get an uploaded file with no associated background task (or vice-versa).

(The background task may involve its own transactions when dequeued later, and spawn further background tasks, etc)