Perhaps mostly in terms of genesis, but also sustainability and even given theoretical evolutionary differences for hypothetical aliens.
But genesis is really the only discussion that matters. Which is also very true for those that believe that there is a good possibility for alien Life.
The math is beyond me to do, but I once got into a conversation with Claude that sought to find the probable distance of the nearest exoplanet that has possible Earth like conditions matching only a couple of additional factors that aren't commonly considered. Whereas I have dozens more. Claude's estimation was that the nearest such planet would be over two million light years away.
Another conversation sought to understand the probability of an exact replica of this solar system somewhere else in the Universe. That probability is zero.