The Great Filter Comes for Us All
blog.codinghorror.com
blog.codinghorror.com
The sci-fi novel Blood Music [0] (expanded from a short-story with the same title) focuses on this concept.
This is especially true if you relax "intelligence" into something more like "computation." For example, your immune system is in a long-running cryptographic (or at least combinatoric) struggle against most other nanobots on the planet, not just in terms of inherited traits, but also during your own lifetime.