Why even write this, by your own admission, cherry picking the negative and making assumptions about dishonesty?
Why even write this, by your own admission, cherry picking the negative and making assumptions about dishonesty?
1. Research shows optimal body fat is closer to 13%. Levels as low as 6% are not supported by studies as beneficial for longevity.
2. Comments about Bryan’s pale appearance aren’t mocking but a valid observation. Pale skin, low body temperature, and a very low heart rate can indicate circulatory issues. While lowering heart rate is beneficial, it follows a U-shaped curve, where excessively low rates—especially during rest—can pose risks, as seen in some ultra-endurance athletes who pass away in their sleep.
3. Bryan’s most concerning stats are some of his heart function measurements where some chronologically age at that of a 70+ year-old. With the average male life expectancy in the U.S. at 73.2 years, his heart may already be near its limit. My hunch is that Bryan focuses heavily on lowering heart rate, body temperature, and blood pressure to counter these poor metrics and reduce risks of heart attack or stroke. However, over-optimization could lead to unintended harm.
I respect Bryan and admire his dedication to health and longevity. His stance against alcohol and on optimizing individual organs may lead to saving millions of lives, as could his focus on extending life in light of AGI. However, there’s a risk of a Greek tragedy, where his pursuit of longevity could become his downfall. I hope this isn’t the case because Bryan is a net positive for humanity, and his efforts have the potential to transform lives.
This is the best I'm seeing atm. https://www.medicinenet.com/how_long_do_you_need_to_fast_for...
Most of the studies we see in IF and autophagy are mouse studies. It isn't to say fasting doesn't result in autophagy in humans, just that the time window most IF practitioners use is not long enough.
Like, if you want a car to still be roadworthy in 20 years, how often do you drive it? Not never, not all the time. You want the little old lady who takes it to the shop once a week.