I have also been taking B5 as both calcium pantothenate at 500 mg/day and also as pantethine at 300 mg/day for years, neither of which has done anything either in this context.
Similarly, B12 hasn't visibly helped either.
I suspect that copper is the issue with me.
The lowest dose of MitoQ, a 5 mg capsule per day, had lowered my blood pressure significantly after a month of use, well below normal, approaching an unsafe low. Moreover, it took another month after discontinuation of MitoQ for the blood pressure to normalize. I shudder to think how much more powerful SkQ1 would be if taken orally. My first impression is that SkQ1 seems more relevant for local use than for systemic use.