I finally got around to trying this out right now. Here's how to run it using uvx (so you don't need to install anything first):

    uvx --from open-interpreter interpreter

I took the simplest route and pasted in an OpenAI API key, then I typed:

    find largest files on my desktop

It generated a couple of chunks of Python, asked my permission to run them, ran them and gave me a good answer.

Here's the transcript: https://gist.github.com/simonw/f78a2ebd2e06b821192ec91963995...