But what if it's possible to alter your influential genes, through some powerful mechanism? Whether it be through insane willpower or anything else. In that case, you have an analogy like something like artificial general intelligence or recursive self-improvement. We get to approach the discussion of questioning natural values and instinctive goals with this line of inquiry. We get to eventually question the metaphysics of God, morality, and aesthetics, by introducing fantastic elements like radical self-modification.