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Comment by bluSCALE4 | Hacker News Reader

Most kill you. If I didn't misread articles on ozempic, they can cause digestive problems where food rots in your stomach. Bad depression was another side effect which blows my mind since you'd think looking better would make you feel great. And these were the minor things.

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> digestive problems where food rots in your stomach

I assume you mean gastroparesis - this is an extremely rare side effect

> Bad depression

Again, pretty rare side effect.

If you think these are the minor things I'm confused as to what you think the major side effects are.

Gastroparesis is literally the method of action of GLP1 agonists. It slows gastric motility. Gastroparesis is literally slowed motility of the stomach (where 20% of food stays in your stomach after 4 hours). It doesn't matter why, that is the literal diagnostic criteria, ergo it literally causes gastroparesis.

Your position does not match that of medical researchers.

https://jamanetwork.com/journals/jama/fullarticle/2810542

https://pmc.ncbi.nlm.nih.gov/articles/PMC10874596/

https://pubmed.ncbi.nlm.nih.gov/38443105/

Or more plainly worded

https://www.healthline.com/health-news/ozempic-wegovy-stomac...

Some people develop permanent gastroparesis.

I don't think you realize the amount of people have taken Ozempic or similar drug. I'm lucky enough that I haven't had issues with body weight, but if I believe the stats (and my observations in real world confirm it), about 15% of adults are on it.

If it was "killing people", we would be seeing it literally everywhere. We're not talking about a small scale 50K+ observation... we're talking about literal millions.

This says 6% are currently on a GLP-1 drug and 15% have ever taken one in their life:

https://amp.cnn.com/cnn/2024/05/10/health/ozempic-glp-1-surv...

Fair, I remembered my stats wrong. But it's still 15M people in US that are actively on it. That's a lot of people.

Really just meant it kills you if you plan on using it as a lifelong solution. I don't have an obesity problem but if I did, this is one of those drugs I'd journal about daily to keep track of how it's affecting me.

Where is any source about it, other than “it just feels wrong, people shouldn’t cheat their way out of obesity”? Sorry for being obtuse, but I have very close friends for whom it changed their lives.

> Bad depression was another side effect

What? Ozempic has been noted for its mild _anti_ depression activity.

both can be true. it can reduce depression in 60% of people and increase it in 10%

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