Last time I tried nixos-gnome and mouse-scrolled a window in the settings app, it got caught on a slider, started adjusting the slider instead, and I couldn't tell what the original value was, and when I searched about it, there's no setting to not adjust sliders with mouse scrolling. Don't get me started about copy and paste being different keystrokes in a terminal. Windows has the same problem and many more.
Well, phones don't have those exact problems, but you get the idea. It's little papercuts everywhere, sometimes caused by settings that could fix them but have the wrong defaults.
While these are fantastic, I think most people would find these as UX downgrades from Google Pixel's stock OS.