I try and maintain 100 char width in most code, because I feel like it makes people more concise.

I’m curious on several statements you made, please take these as genuine and well intended questions:

what’s wrong with two space indent?

Would a bigger monitor with higher DPI solve some of these issues?

Have you considered a horizontal scroll wheel or similar? I think this is a Band-Aid to a bad pattern, but may be a legitimate option

You may appreciate python PEP8, which discusses things like highly nested code and functions being considered bad. I first followed PEP8 kicking and screaming, but I think it forced me to remove some bad programming habits and I now lint check my code habitually.