It's mainly because of the restrictions of different mediums, for example Alyx has much less enemy density, very narrow corridor-based levels made for limited movement of real human bodies and environments, a lot more emphasis on interactivity with the world and objects that would lose their meaning if replaced with "press F to $WHATEVER" buttons. It might be pretty mediocre as a flat-screen game.
I guess it may still be worth it if you desperately need something Half Life and want to see the story, though for that I'd rather watch it on YouTube, or just rent a VR headset for a month.