It’s already happened, for instance there are multiple blocklists that try to remove as many furries as possible (which personally is a benefit, although you may think differently). We also have more political ones, mostly anti-“right wing” as bsky trends more “left”. The more extreme elements of Twitter were the first to evacuate, so it’s no surprise that they’re already attempting to rebuild their algorithmically defined echo chambers. Dissenting opinions cause 3d6 psychic damage, after all.