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> it would slow down and even kill a lot of infectious microbes

I wouldn't count on it killing them. The cryoprotectants in the frog's body don't discriminate; they'll protect foreign bacteria just as well as the frog's cells.

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I should of elaborated, many of the issues associated with,"conventional hibernation" have to do with lethal infections aquired externaly while hibernating, damp, cold, ....mold as to the cryoprotectants ,side protecting microbes, clearly gut microbes and other internal flora ,would benifit......but ,big but, would a sneeky cryosuspension routine also include a freeze and clense cycle?, why not! and easy enough to verify,right!

I wonder what happens to the gut bacteria ? Do they also freeze and get thawed ? If so, are those bacterium also having a special adaptation, or is it a function of the host ?

I would imagine the frog's internal ecosystem has co-evolved with lots of bacteria that can also be frozen solid.

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