Is NAD your best shot at longevity?

AI summary:

1. NAD+ Injections for Longevity: NAD (nicotinamide adenine dinucleotide) is a molecule essential for cell function and longevity. Injecting NAD+ has become popular for improving metabolism, brain function, and energy levels, with some users reporting benefits like better sleep, improved workout performance, and increased vitality.

2. Celebrity and Athlete Endorsements: NAD+ injections are being used by elite athletes, such as Premier League footballers, and endorsed by celebrities. It's said to enhance endurance and improve performance in sports.

3. Scientific Backing: Research by Prof Shin-ichiro Imai suggests NAD can delay aging and improve quality of life, though there is debate on the efficacy of injections versus oral supplements. Imai supports NMN supplements as a more efficient way to boost NAD within cells.

4. Market Growth: The NAD market is rapidly expanding, with at-home injectable kits now available. These products are costly, ranging from £195 for two weeks to £395 for two months, but demand is increasing.

5. Concerns and Individual Dosing: High doses of NAD+ IV drips are cautioned against by some doctors due to side effects like nausea and headaches. Patients are advised to monitor and adjust doses for optimal results.

6. Lifestyle Factors: NAD levels naturally decrease with age, and lifestyle choices like stress, alcohol consumption, and poor diet can further deplete it. Boosting NAD levels might be a lifelong commitment for maintaining health and mitigating aging.

7. Reported Benefits: Users of NAD+ injections have reported increased energy, improved sleep, weight loss, and potential relief from conditions like Parkinson’s, menopause, and long Covid.

8. Long-term Use and Maintenance: While NAD injections may offer short-term boosts, many users eventually switch to oral supplements for maintenance due to the inconvenience of frequent injections.

9. Caution Against Miraculous Claims: Experts advise against viewing NAD as a miracle cure and recommend blood and genetic testing before use. Results may be more gradual and cellular, such as improving muscle insulin sensitivity, rather than immediate visible changes.

Head-to-head comparisons of different precursors (NR, NMN, NAM, niacin) are lacking.

Niacin is cheap.